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Product Information

Mevacor is the brand name for the generic drug Lovastatin. Mevacor (Lovastatin) is the first cholesterol-lowering drug to be approved by the FDA. It works by reducing the LDL ‘bad’ cholesterol and triglyceride levels in the blood and raising the HDL ‘good’ cholesterol level. It functions as an enzyme blocker (HMG-CoA reductase inhibitor) which prevents the production of cholesterol by the liver.

Mevacor is proven to reduce the risk of coronary artery disease events, such as heart attack or angina (chest pain). Besides lowering LDL cholesterol levels, it retards progression and may even reverse coronary artery disease. Reducing cholesterol and triglycerides help prevent strokes and heart attacks. Mevacor should be used in conjunction to proper diet and is recommended only after non-drug treatment options have not been fully successful at lowering cholesterol.  

  

How to Use

Mevacor should be taken orally once daily or as directed by the doctor. Use this medication regularly in order to get the maximum benefit and preferably use it at the same time each day. Mevacor may take up to 4 weeks before the full benefit of the drug comes into effect. Mevacor is used in adults and children (10 years of age and older). Use the medicine regularly once started and do not stop without consulting your doctor. 

  

Side Effects

The Initial Adjustment: As your body adjusts to the medication, you may have minor side effects for first few days likeConstipation Diarrhea Flatulence Heartburn Headache Insomnia.

   

Consult a Doctor

Consult your doctor if these effects persist or you experience abdominal pain or cramps, blurred vision, dizziness, fatigue, itching, muscle pain or cramps, rash, yellowing of the skin or eyes. Moreover, notify your doctor immediately if you experience muscle weakness, tenderness, numbness; brown or dark urine; nausea, vomiting and abdominal pain. Rare cases of muscle inflammation (myositis) and breakdown have been reported with Mevacor.

  

Drug InteractionUse Mevacor only after judging all possibilities of drug interaction. Consult your doctor and inform about all the prescription and nonprescription drugs you use. Severe muscle breakdown and kidney failure have been reported when Mevacor is used together with gemfibrozil (Lopid). There is also risk of muscle breakdown by drug interaction when Mevacor is used along with drugs such as cyclosporine (Sandimmune), erythromycin and nicotinic acid. It is recommendable that you avoid taking alcohol when using Mevacor. Mevacor when used along with the following drugs can be cause fatal reactions: -Azole antifungals (e.g., itraconazole, ketoconazole) -Delavirdine -HIV protease inhibitors (e.g., ritonavir, amprenavir, lopinavir) -Certain macrolide antibiotics (e.g., erythromycin, clarithromycin, troleandomycin) -Mibefradil, nefazodone, and telithromycin.  

  

Precautions

Mevacor should be prescribed and used by young girls only after they have had their menstrual periods for at least one year before starting this medication.

  

Limit the amount of grapefruit or grapefruit juice you may eat or drink (less than 1 quart a day) while being treated with this medication, unless specifically directed otherwise. Grapefruit juice may increase the amount of certain medications in your bloodstream.

  

This drug is not recommended for use in children, only 10 years of age and older.

  

Mevacor should be used only after consulting a doctor if you have liver disease.

  

Inform your healthcare provider if you suffering from conditions like diabetes that is not well-controlled; kidney disease, under-active thyroid, chronic muscular disease and blood disorder.

  

Mevacor has been included in the FDA category X for pregnancy, which means that it can be cause birth defects in an unborn child. So, the drug should not be used by expecting mothers or those planning pregnancy.

  

Consult your doctor if you are a lactating mother; because it is not known whether the drug passes on to the milk.

  

Inform your doctor if you drink alcoholic beverages.

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Lipitor is used with diet changes (restriction of cholesterol and fat intake) to reduce the amount of cholesterol and certain fatty substances in your blood. Accumulation of cholesterol and fats along the walls of your arteries (a process known as atherosclerosis) decreases blood flow and, therefore, the oxygen supply to your heart, brain, and other parts of your body. Lowering your blood level of cholesterol and fats may help to prevent heart disease, angina (Chest pain), strokes, and heart attacks. 

Lipitor comes as a tablet to take it orally. It is usually taken once a day with or without food. To help you remember to take Lipitor, take it around the same time every day. Your doctor may start you on a low dose of Lipitor and gradually increase your dose. Continue to take Lipitor even if you feel well. Do not stop taking Lipitor without talking to your doctor. Eat a low-cholesterol, low-fat diet.

Do not take Lipitor without first talking to your doctor if you have liver disease. Before taking Lipitor, tell your doctor if you have a chronic muscular disease, require major surgery, or have a blood disorder. You may not be able to take Lipitor, or you may require a dosage adjustment or special monitoring during treatment if you have any of the conditions listed above. Lipitor is in the FDA pregnancy category X. This means that Lipitor is known to cause birth defects if it is taken during pregnancy. Do not take Lipitor if you are pregnant or could become pregnant during treatment. It is not known whether Lipitor passes into breast milk. Do not take this medication without first talking to your doctor if you are breast-feeding a baby.  

Take the missed dose as soon as you remember. However, if it is almost time for the next regularly scheduled dose, skip the missed dose and take the next one as directed. Do not take a double dose of this medication unless otherwise directed by your doctor.  

Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom). Throw away any medication that is outdated or no longer needed. Talk to your pharmacist about the proper disposal of your medication. 

Seek emergency medical attention if an overdose is suspected. The symptoms of an Lipitor overdose are not known.

Alcohol and Lipitor can both be damaging to the liver. Alcohol should be used only in moderation. Discuss the use of alcohol with your doctor so that the potential for liver problems can be determined. Grapefruit and grapefruit juice may interact with Lipitor. The interaction could lead to potentially dangerous effects.